SDHC antibody (AA 1-169)

Catalog No. ABIN520106

There are 2+ publications for this product available. The Mouse Monoclonal anti-SDHC antibody is suitable to detect SDHC in samples from Human. It has been validated for WB and ELISA.

Quick Overview for SDHC antibody (AA 1-169) (ABIN520106)

Target: SDHC (Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SDHC antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 3G7

Product Details anti-SDHC Antibody

Binding Specificity: AA 1-169

Purpose: Mouse monoclonal antibody raised against a full length recombinant SDHC.

Sequence: MAALLLRHVG RHCLRAHFSP QLCIRNAVPL GTTAKEEMER FWNKNIGSNR PLSPHITIYS WSLPMAMSIC HRGTGIALSA GVSLFGMSAL LLPGNFESYL ELVKSLCLGP ALIHTAKFAL VFPLMYHTWN GIRHLMWDLG KGLKIPQLYQ SGVVVLVLTV LSSMGLAAM

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SDHC (AAH33626, 1 a.a. ~ 169 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SDHC antibody (ABIN520106)

Lemarie, Huc, Pazarentzos, Mahul-Mellier, Grimm: "Specific disintegration of complex II succinate:ubiquinone oxidoreductase links pH changes to oxidative stress for apoptosis induction." in: Cell death and differentiation, Vol. 18, Issue 2, pp. 338-49, (2011) (PubMed).

Lemarie, Grimm: "Mutations in the heme b-binding residue of SDHC inhibit assembly of respiratory chain complex II in mammalian cells." in: Mitochondrion, Vol. 9, Issue 4, pp. 254-60, (2009) (PubMed).

Target Details for SDHC

Target: SDHC (Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC))

Alternative Name: SDHC

Background: Full Gene Name: succinate dehydrogenase complex, subunit C, integral membrane protein, 15 kDa
Synonyms: CYB560,CYBL,PGL3,QPS1,SDH3

Gene ID: 6391