SQSTM1 antibody (Sequestosome 1) (AA 1-440)

Details for Product anti-SQSTM1 Antibody No. ABIN522359, Supplier: Log in to see
Antigen
  • SQSTM1
  • sqstm1
  • MGC79491
  • A170
  • OSIL
  • PDB3
  • ZIP3
  • p60
  • p62
  • p62B
  • OSF-6
  • Osi
  • STAP
  • ZIP
  • sb:cb621
  • zgc:85784
  • sequestosome 1
  • sqstm1 protein
  • SQSTM1
  • LOC100342157
  • sqstm1
  • Sqstm1
Alternatives
anti-Human SQSTM1 antibody for Dot Blot
Epitope
AA 1-440, full length
51
40
23
19
19
18
18
17
17
17
15
14
11
11
8
6
6
5
5
4
4
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
306
133
100
8
5
5
5
4
4
2
2
2
2
2
1
1
1
1
1
1
Host
Mouse
252
47
4
3
Clonality (Clone)
Monoclonal ()
Conjugate
This SQSTM1 antibody is un-conjugated
17
16
16
10
10
10
7
7
7
5
5
4
4
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
245
122
83
82
65
65
36
35
20
14
13
4
4
2
2
Options
Supplier
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Available images

Immunogen SQSTM1 (AAH03139.1, 1 a.a. ~ 440 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: MASLTVKAYL LGKEDAAREI RRFSFCCSPE PEAEAEAAAG PGPCERLLSR VAALFPALRP GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KDDIFRIYIK EKKECRRDHR PPCAQEAPRN MVHPNVICDG CNGPVVGTRY KCSVCPDYDL CSVCEGKGLH RGHTKLAFPS PFGHLSEGFS HSRWLRKVKH GHFGWPGWEM GPPGNWSPRP PRAGEARPGP TAESASGPSE DPSVNFLKNV GESVAAALSP LGIEVDIDVE HGGKRSRLTP VSPESSSTEE KSSSQPSSCC SDPSKPGGNV EGATQSLAEQ MRKIALESEG RPEEQMESDN CSGGDDDWTH LSSKEVDPST GELQSLQMPE SEGPSSLDPS QEGPTGLKEA ALYPHLPPEA DPRLIESLSQ MLSMGFSDEG GWLTRLLQTK NYDIGAALDT IQYSKHPPPL
Clone 1C9
Isotype IgG3 kappa
Cross-Reactivity Human
Alternative Name SQSTM1 (SQSTM1 Antibody Abstract)
Background Full Gene Name: sequestosome 1
Synonyms: A170,OSIL,PDB3,ZIP3,p60,p62,p62B
Gene ID 8878
Pathways NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
ELISA image for anti-SQSTM1 antibody (Sequestosome 1) (AA 1-440) (ABIN522359) Detection limit for recombinant GST tagged SQSTM1 is approximately 3ng/ml as a captur...
 image for anti-SQSTM1 antibody (Sequestosome 1) (AA 1-440) (ABIN522359) Western Blot detection against Immunogen (74.14 KDa) .
Product cited in: Myeku, Clelland, Emrani, Kukushkin, Yu, Goldberg, Duff: "Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling." in: Nature medicine, Vol. 22, Issue 1, pp. 46-53, 2016 (PubMed).

Notte, Ninane, Arnould, Michiels: "Hypoxia counteracts taxol-induced apoptosis in MDA-MB-231 breast cancer cells: role of autophagy and JNK activation." in: Cell death & disease, Vol. 4, pp. e638, 2013 (PubMed).

Cosse, Rommelaere, Ninane, Arnould, Michiels: "BNIP3 protects HepG2 cells against etoposide-induced cell death under hypoxia by an autophagy-independent pathway." in: Biochemical pharmacology, Vol. 80, Issue 8, pp. 1160-9, 2010 (PubMed).

Kirkin, Lamark, Sou, Bjørkøy, Nunn, Bruun, Shvets, McEwan, Clausen, Wild, Bilusic, Theurillat, Øvervatn, Ishii, Elazar, Komatsu, Dikic, Johansen: "A role for NBR1 in autophagosomal degradation of ubiquitinated substrates." in: Molecular cell, Vol. 33, Issue 4, pp. 505-16, 2009 (PubMed).