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LARP6 antibody (AA 1-491)

LARP6 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
Catalog No. ABIN527496
  • Target See all LARP6 Antibodies
    LARP6 (La Ribonucleoprotein Domain Family, Member 6 (LARP6))
    Binding Specificity
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    AA 1-491
    Reactivity
    • 27
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 26
    • 1
    Mouse
    Clonality
    • 27
    Polyclonal
    Conjugate
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    This LARP6 antibody is un-conjugated
    Application
    • 21
    • 17
    • 14
    • 14
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purpose
    Mouse polyclonal antibody raised against a full-length human LARP6 protein.
    Sequence
    MAQSGGEARP GPKTAVQIRV AIQEAEDVDE LEDEEEGAET RGAGDPARYL SPGWGSASEE EPSRGHSGTT ASGGENERED LEQEWKPPDE ELIKKLVDQI EFYFSDENLE KDAFLLKHVR RNKLGYVSVK LLTSFKKVKH LTRDWRTTAH ALKYSVVLEL NEDHRKVRRT TPVPLFPNEN LPSKMLLVYD LYLSPKLWAL ATPQKNGRVQ EKVMEHLLKL FGTFGVISSV RILKPGRELP PDIRRISSRY SQVGTQECAI VEFEEVEAAI KAHEFMITES QGKENMKAVL IGMKPPKKKP AKDKNHDEEP TASIHLNKSL NKRVEELQYM GDESSANSSS DPESNPTSPM AGRRHAATNK LSPSGHQNLF LSPNASPCTS PWSSPLAQRK GVSRKSPLAE EGRLNCSTSP EIFRKCMDYS SDSSVTPSGS PWVRRRRQAE MGTQEKSPGT SPLLSRKMQT ADGLPVGVLR LPRGPDNTRG FHGHERSRAC V
    Cross-Reactivity
    Human
    Characteristics
    Antibody reactive against mammalian transfected lysate.
    Immunogen
    LARP6 (NP_060827, 1 a.a. ~ 491 a.a) full-length human protein.
    Top Product
    Discover our top product LARP6 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Blackstock, Higashi, Sukhanov, Shai, Stefanovic, Tabony, Yoshida, Delafontaine: "Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA." in: The Journal of biological chemistry, Vol. 289, Issue 11, pp. 7264-74, (2014) (PubMed).

    Wang, Stefanovic: "Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane." in: PLoS ONE, Vol. 9, Issue 10, pp. e108870, (2014) (PubMed).

    Manojlovic, Blackmon, Stefanovic: "Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis." in: PLoS ONE, Vol. 8, Issue 6, pp. e65897, (2013) (PubMed).

    Vukmirovic, Manojlovic, Stefanovic: "Serine-threonine kinase receptor-associated protein (STRAP) regulates translation of type I collagen mRNAs." in: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3893-906, (2013) (PubMed).

    Manojlovic, Stefanovic: "A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs." in: RNA (New York, N.Y.), Vol. 18, Issue 2, pp. 321-34, (2012) (PubMed).

    Challa, Stefanovic: "A novel role of vimentin filaments: binding and stabilization of collagen mRNAs." in: Molecular and cellular biology, Vol. 31, Issue 18, pp. 3773-89, (2011) (PubMed).

    Cai, Fritz, Stefanovic, Stefanovic: "Binding of LARP6 to the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen." in: Journal of molecular biology, Vol. 395, Issue 2, pp. 309-26, (2010) (PubMed).

    Cai, Fritz, Stefanovic, Stefanovic: "Nonmuscle myosin-dependent synthesis of type I collagen." in: Journal of molecular biology, Vol. 401, Issue 4, pp. 564-78, (2010) (PubMed).

  • Target
    LARP6 (La Ribonucleoprotein Domain Family, Member 6 (LARP6))
    Alternative Name
    LARP6 (LARP6 Products)
    Synonyms
    im:7142825 antibody, wu:fa55b04 antibody, ACHN antibody, 5430431G03Rik antibody, AI552438 antibody, Achn antibody, RGD1308414 antibody, La ribonucleoprotein domain family, member 6b antibody, La ribonucleoprotein domain family member 6 antibody, La ribonucleoprotein domain family, member 6 antibody, larp6b antibody, LARP6 antibody, Larp6 antibody
    Background
    Full Gene Name: La ribonucleoprotein domain family, member 6
    Synonyms: ACHN,FLJ11196
    Gene ID
    55323
    NCBI Accession
    NM_018357
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