POLD4 antibody (AA 1-34)

Catalog No. ABIN528317

Product Details anti-POLD4 Antibody

Target: POLD4 (Polymerase (DNA-Directed), delta 4, Accessory Subunit (POLD4))

Binding Specificity: AA 1-34

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This POLD4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a full length recombinant POLD4.

Sequence: MGRKRLITDS YPVVKRREGP AGHSKGELAP ELGL

Cross-Reactivity: Human

Immunogen: POLD4 (AAH01334, 1 a.a. ~ 34 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2B11

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In ascites fluid

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-POLD4 antibody (ABIN528317)

Huang, Akashi, Masuda, Kamiya, Takahashi, Suzuki: "Roles of POLD4, smallest subunit of DNA polymerase delta, in nuclear structures and genomic stability of human cells." in: Biochemical and biophysical research communications, Vol. 391, Issue 1, pp. 542-6, (2010) (PubMed).

Huang, Tomida, Masuda, Arima, Cao, Kasahara, Osada, Yatabe, Akashi, Kamiya, Takahashi, Suzuki: "Regulation of DNA polymerase POLD4 influences genomic instability in lung cancer." in: Cancer research, Vol. 70, Issue 21, pp. 8407-16, (2010) (PubMed).

Zhang, Zhou, Trusa, Meng, Lee, Lee: "A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta." in: The Journal of biological chemistry, Vol. 282, Issue 21, pp. 15330-40, (2007) (PubMed).

Target Details for POLD4

Target: POLD4 (Polymerase (DNA-Directed), delta 4, Accessory Subunit (POLD4))

Alternative Name: POLD4 (POLD4 Products)

Synonyms: 2410012M21Rik antibody, AI463381 antibody, AW060307 antibody, Polds antibody, p12 antibody, POLDS antibody, DNA polymerase delta 4, accessory subunit antibody, polymerase (DNA-directed), delta 4 antibody, POLD4 antibody, Pold4 antibody

Background: Full Gene Name: polymerase (DNA-directed), delta 4
Synonyms: POLDS,p12

Gene ID: 57804

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA