TNFRSF10A antibody (AA 1-20)

Catalog No. ABIN531956

Product Details anti-TNFRSF10A Antibody

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Binding Specificity: AA 1-20

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF10A antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Purpose: Mouse monoclonal antibody raised against synthetic peptide of TNFRSF10A.

Cross-Reactivity: Human

Immunogen: A synthetic peptide corresponding to amino acids 1-20 of human TNFRSF10A.

Clone: 32A1380

Isotype: IgG1

Application Details

Application Notes: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.05 % BSA, 0.05 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TNFRSF10A antibody (ABIN531956)

Kroll, Bommiasamy, Boissy, Hernandez, Nickoloff, Mestril, Caroline Le Poole: "4-Tertiary butyl phenol exposure sensitizes human melanocytes to dendritic cell-mediated killing: relevance to vitiligo." in: The Journal of investigative dermatology, Vol. 124, Issue 4, pp. 798-806, (2005) (PubMed).

Liu, Yue, Khuri, Sun: "p53 upregulates death receptor 4 expression through an intronic p53 binding site." in: Cancer research, Vol. 64, Issue 15, pp. 5078-83, (2004) (PubMed).

Ren, Wagner, Knee, Aza-Blanc, Nasoff, Deveraux: "Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle." in: Molecular biology of the cell, Vol. 15, Issue 11, pp. 5064-74, (2004) (PubMed).

Chen, Kandasamy, Srivastava: "Differential roles of RelA (p65) and c-Rel subunits of nuclear factor kappa B in tumor necrosis factor-related apoptosis-inducing ligand signaling." in: Cancer research, Vol. 63, Issue 5, pp. 1059-66, (2003) (PubMed).

Shigeno, Nakao, Ichikawa, Suzuki, Kawakami, Abiru, Miyazoe, Nakagawa, Ishikawa, Hamasaki, Nakata, Ishii, Eguchi: "Interferon-alpha sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-kappa B inactivation." in: Oncogene, Vol. 22, Issue 11, pp. 1653-62, (2003) (PubMed).

Target Details for TNFRSF10A

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Alternative Name: CD261 / TRAILR1 (TNFRSF10A Products)

Synonyms: APO2 antibody, CD261 antibody, DR4 antibody, TRAILR-1 antibody, TRAILR1 antibody, TNFRSF10A antibody, TNF receptor superfamily member 10a antibody, tumor necrosis factor receptor superfamily member 26 antibody, tumor necrosis factor receptor superfamily, member 10a antibody, TNFRSF10A antibody, LOC510798 antibody

Gene ID: 8797

Pathways: Apoptosis, Positive Regulation of Endopeptidase Activity