TARDBP antibody (AA 350-414)
TARDBP
Reactivity: Human, Mouse, Zebrafish (Danio rerio), Chicken, Monkey, Xenopus laevis, Frog, Primate
WB
Host: Rabbit
Polyclonal
unconjugated
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Target
See all TARDBP Antibodies
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TARDBP
(TAR DNA Binding Protein (TARDBP))
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Binding Specificity
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AA 350-414
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Reactivity
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Human, Mouse, Zebrafish (Danio rerio), Chicken, Monkey, Xenopus laevis, Frog, Primate
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Host
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Rabbit
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Clonality
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Polyclonal
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Conjugate
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This TARDBP antibody is un-conjugated
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Application
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Western Blotting (WB)
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Purpose
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Rabbit polyclonal antibody raised against synthetic peptide of TARDBP.
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Cross-Reactivity
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Chicken, Frog, Human, Monkey, Mouse, Primate, Xenopus laevis, Zebrafish (Danio rerio)
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Characteristics
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Antibody Reactive Against Synthetic Peptide.
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Immunogen
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A synthetic peptide corresponding to amino acids 350-414 of human TARDBP.
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Top Product
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Discover our top product TARDBP Primary Antibody
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Application Notes
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Western Blot (0.5-2 μg/mL)
The optimal working dilution should be determined by the end user.
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Restrictions
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For Research Use only
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Format
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Liquid
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Buffer
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In Tris-glycine, 150 mM NaCl (0.05 % sodium azide)
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Preservative
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Sodium azide
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Precaution of Use
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This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
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4 °C
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Storage Comment
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Store at 4°C. Do not freeze.
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De Marco, Lomartire, Mandili, Lupino, Buccinnà, Ramondetti, Moglia, Novelli, Piccinini, Mostert, Rinaudo, Chiò, Calvo: "Reduced cellular Ca(2+) availability enhances TDP-43 cleavage by apoptotic caspases." in: Biochimica et biophysica acta, Vol. 1843, Issue 4, pp. 725-34, (2014) (PubMed).
Geser, Brandmeir, Kwong, Martinez-Lage, Elman, McCluskey, Xie, Lee, Trojanowski: "Evidence of multisystem disorder in whole-brain map of pathological TDP-43 in amyotrophic lateral sclerosis." in: Archives of neurology, Vol. 65, Issue 5, pp. 636-41, (2008) (PubMed).
Mackenzie, Bigio, Ince, Geser, Neumann, Cairns, Kwong, Forman, Ravits, Stewart, Eisen, McClusky, Kretzschmar, Monoranu, Highley, Kirby, Siddique, Shaw, Lee, Trojanowski: "Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations." in: Annals of neurology, Vol. 61, Issue 5, pp. 427-34, (2007) (PubMed).
Cairns, Neumann, Bigio, Holm, Troost, Hatanpaa, Foong, White, Schneider, Kretzschmar, Carter, Taylor-Reinwald, Paulsmeyer, Strider, Gitcho, Goate, Morris, Mishra, Kwong, Stieber, Xu, Forman et al.: "TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. ..." in: The American journal of pathology, Vol. 171, Issue 1, pp. 227-40, (2007) (PubMed).
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Target
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TARDBP
(TAR DNA Binding Protein (TARDBP))
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Alternative Name
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TARDBP (TARDBP Products)
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Synonyms
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TARDBP antibody, TDP43 antibody, DKFZp459I2127 antibody, tardbp antibody, ALS10 antibody, TDP-43 antibody, 1190002A23Rik antibody, C85084 antibody, Tdp43 antibody, wu:fb77f02 antibody, wu:fc52g10 antibody, TAR DNA binding protein antibody, Tardbp protein antibody, TAR DNA binding protein L homeolog antibody, TAR DNA-binding protein 43-like antibody, TARDBP antibody, tardbp antibody, tardbp.L antibody, Tardbp antibody, LOC100621383 antibody
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Gene ID
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23435
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Pathways
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Positive Regulation of Peptide Hormone Secretion
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