IRS2 antibody

Catalog No. ABIN541009

Product Details anti-IRS2 Antibody

Target: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRS2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Dot Blot (DB), Immunoprecipitation (IP)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of IRS2.

Specificity: This antibody recognizes ~180 KDa of human IRS2.

Cross-Reactivity: Human, Mouse, Rat

Immunogen: A synthetic peptide corresponding to residues surrounding S731 of human IRS2.

Isotype: IgG

Application Details

Application Notes: Western Blot (0.1-1 μg/mL)
ELISA (0.01-0.1 μg/mL)
Immunoprecipitation (2-5 μg/mL)
Immunohistochemistry (0.5-2 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In TBS, pH 7.2 (BSA, 10 % Proclin300)

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-IRS2 antibody (ABIN541009)

Li, Soos, Li, Wu, Degennaro, Sun, Littman, Birnbaum, Polakiewicz: "Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101)." in: The Journal of biological chemistry, Vol. 279, Issue 44, pp. 45304-7, (2004) (PubMed).

Target Details for IRS2

Target: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Alternative Name: IRS2 (IRS2 Products)

Synonyms: IRS2 antibody, si:dkeyp-24d6.1 antibody, IRS-2 antibody, 4PS antibody, Irs-2 antibody, insulin receptor substrate 2 antibody, insulin receptor substrate 2a antibody, insulin receptor substrate 2b antibody, IRS2 antibody, irs2a antibody, irs2b antibody, Irs2 antibody

Gene ID: 8660

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process