Bone Morphogenetic Protein 7 (BMP7) (AA 280-431) antibody

Details for Product No. ABIN551087
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms bmp-7, bmp7, op-1, BMP7, zgc:153025, OP-1, OP1, BMP-7, fb83f09, wu:fb83f09
Epitope
AA 280-431
(16), (9), (7), (6), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(157), (43), (40), (14), (13), (13), (13), (1), (1)
Host
Rabbit
(106), (50), (5), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(9), (5), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(124), (77), (40), (17), (10), (9), (9), (7), (4), (4), (3), (3), (3), (2), (2)
Pubmed 6 references available
Quantity 0.1 mL
Shipping to United States (Change)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN551087
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Recombinant fragment corresponding to a region within amino acids 280 and 431 of BMP7
Isotype IgG
Predicted Reactivity Human (100%), Dog (100%), Pig (100%), Bovine (100%)
Characteristics Cellular Localization: Secreted
Purification Purified by antigen-affinity chromatography..
Alternative Name BMP7
Background The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq]
Synonyms: OP-1 antibody, BMP7 antibody, bone morphogenetic protein 7 antibody, osteogenic protein 1 antibody, BMP-7 antibody
Molecular Weight 49 kDa
UniProt P18075
Research Area Organogenesis, Cell Cycle, Extracellular Matrix, Signaling, Hormones, Cytokines
Comment

Positive Controls: Target recombinant protein

Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Guan, Burgess, Robinson et al.: "Phagocytic cell molecules that bind the collagen-like region of C1q. Involvement in the C1q-mediated enhancement of phagocytosis." in: The Journal of biological chemistry, Vol. 266, Issue 30, pp. 20345-55, 1991 (PubMed).

Guan, Robinson, Goodman et al.: "Cell-surface protein identified on phagocytic cells modulates the C1q-mediated enhancement of phagocytosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 152, Issue 8, pp. 4005-16, 1994 (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, 1996 (PubMed).

Nepomuceno, Henschen-Edman, Burgess et al.: "cDNA cloning and primary structure analysis of C1qR(P), the human C1q/MBL/SPA receptor that mediates enhanced phagocytosis in vitro." in: Immunity, Vol. 6, Issue 2, pp. 119-29, 1997 (PubMed).

Tenner: "C1q receptors: regulating specific functions of phagocytic cells." in: Immunobiology, Vol. 199, Issue 2, pp. 250-64, 1999 (PubMed).

Danet, Luongo, Butler et al.: "C1qRp defines a new human stem cell population with hematopoietic and hepatic potential." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 16, pp. 10441-5, 2002 (PubMed).

Validation Images
Did you look for something else?
back to top