Myostatin (MSTN) (AA 60-375) antibody

Details for Product No. ABIN551102
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Antigen
Synonyms GDF-8, GDF8, gdf8, mstn, zgc:109749, Gdf8, NV13143, MSLHP, Cmpt
Epitope
AA 60-375
(12), (8), (8), (6), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(126), (52), (43), (41), (36), (24), (12)
Host
Rabbit
(85), (27), (26), (7), (3), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(14), (8), (6), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1)
Application
Western Blotting (WB)
(95), (71), (36), (30), (28), (10), (8), (2), (1)
Pubmed 2 references available
Quantity 0.1 mL
Shipping to United States (Change)
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Catalog No. ABIN551102
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Immunogen Recombinant fragment corresponding to a region within amino acids 60 and 375 of GDF-8(myostatin)
Isotype IgG
Predicted Reactivity Human (100%), Rhesus Monkey (100%), Chimpanzee (100%)
Characteristics Cellular Localization: Secreted
Purification Purified by antigen-affinity chromatography..
Alternative Name Myostatin
Background The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. [provided by RefSeq]
Synonyms: GDF8 antibody, MSTN antibody, GDF-8 antibody, growth/differentiation factor 8 antibody, growth differentiation factor 8 antibody, myostatin antibody
Molecular Weight 43 kDa
UniProt O14793
Research Area Hormones
Comment

Positive Controls: Target recombinant protein

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Campbell, Kessler, Fambrough: "The alternative carboxyl termini of avian cardiac and brain sarcoplasmic reticulum/endoplasmic reticulum Ca(2+)-ATPases are on opposite sides of the membrane." in: The Journal of biological chemistry, Vol. 267, Issue 13, pp. 9321-5, 1992 (PubMed).

Blackwood, Eisenman: "Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc." in: Science (New York, N.Y.), Vol. 251, Issue 4998, pp. 1211-7, 1991 (PubMed).

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