C-Reactive Protein (CRP) (AA 1-219) antibody

Details for Product No. ABIN551236
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Antigen
Synonyms crp, PTX1, AI255847, Aa1249, Ab1-341, Ab2-196, Ac1-114, Ac1262, Ac2-069, Ba2-693, APCS, 0610010I23Rik, AW743261, C77570, CRP2, CRP4, Crp, ESP1, Hlp, CRP, GRP-CB
Epitope
AA 1-219
(16), (11), (7), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Reactivity
Human
(403), (42), (40), (19), (14), (6), (5), (4), (1), (1)
Host
Rabbit
(205), (119), (83), (36), (6), (5), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(30), (19), (18), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application
Western Blotting (WB)
(282), (213), (60), (46), (22), (20), (20), (19), (15), (12), (11), (9), (8), (7), (7), (6), (6), (5), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 5 references available
Quantity 0.1 mL
Shipping to United States (Change)
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Catalog No. ABIN551236
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Immunogen Recombinant fragment corresponding to a region within amino acids 1 and 219 of C Reactive Protein
Isotype IgG
Characteristics Cellular Localization: Secreted
Purification Purified by antigen-affinity chromatography..
Background The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq]
Synonyms: MGC149895 antibody, MGC88244 antibody, PTX1 antibody, CRP antibody, pentraxin 1 antibody, C-reactive protein antibody, "C-reactive protein, pentraxin-related antibody"
Molecular Weight 25 kDa
UniProt P02741
Research Area Serum/Plasma Proteins, Inflammation
Comment

Positive Controls: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji

Restrictions For Research Use only
Format Liquid
Concentration 0.67 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Duan, Orth, Chinnaiyan et al.: "ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B." in: The Journal of biological chemistry, Vol. 271, Issue 28, pp. 16720-4, 1996 (PubMed).

Thornberry, Rano, Peterson et al.: "A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis." in: The Journal of biological chemistry, Vol. 272, Issue 29, pp. 17907-11, 1997 (PubMed).

Chandler, Cohen, MacFarlane: "Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver." in: The Journal of biological chemistry, Vol. 273, Issue 18, pp. 10815-8, 1998 (PubMed).

Wolf, Green: "Suicidal tendencies: apoptotic cell death by caspase family proteinases." in: The Journal of biological chemistry, Vol. 274, Issue 29, pp. 20049-52, 1999 (PubMed).

Germain, Mathai, Shore: "BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria." in: The Journal of biological chemistry, Vol. 277, Issue 20, pp. 18053-60, 2002 (PubMed).

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