Tryptophan Hydroxylase 1 (TPH1) (AA 206-394) antibody

Details for Product No. ABIN551429
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms tph, tph1, tphD1, TPH, LOC100229598, TPRH, TRPH, Tph, SERGEF
Epitope
AA 206-394
(27), (22), (15), (13), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(128), (87), (65), (29), (28), (19), (14), (5), (4), (3), (2), (1), (1), (1)
Host
Rabbit
(119), (16), (15), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(6), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(114), (48), (46), (29), (21), (17), (11), (6), (6), (4), (1), (1)
Pubmed 3 references available
Quantity 0.1 mL
Shipping to United States (Change)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN551429
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Recombinant fragment contain a sequence corresponding to a region within amino acids 206 and 394 of Tryptophan Hydroxylase
Cross-Reactivity Mouse (Murine)
Predicted Reactivity Human (100%)
Purification Purified by antigen-affinity chromatography..
Alternative Name Tryptophan 5-hydroxylase 1 (TPH1)
Background This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
Synonyms: MGC119994 antibody, TPRH antibody, TRPH antibody, TPH1 antibody, tryptophan hydroxylase (tryptophan 5-monooxygenase) antibody, tryptophan 5-monooxygenase 1 antibody, tryptophan 5-hydroxylase 1 antibody, L-tryptophan hydroxylase antibody, indoleacetic acid-5-hydroxylase antibody, tryptophan hydroxylase 1 antibody
Molecular Weight 51 kDa
UniProt P17752
Research Area Amino Acids, Enzymes, Metabolism
Restrictions For Research Use only
Format Liquid
Concentration 0.49 mg/mL
Buffer 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Susin, Lorenzo, Zamzami et al.: "Molecular characterization of mitochondrial apoptosis-inducing factor." in: Nature, Vol. 397, Issue 6718, pp. 441-6, 1999 (PubMed).

Joza, Susin, Daugas et al.: "Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death." in: Nature, Vol. 410, Issue 6828, pp. 549-54, 2001 (PubMed).

Martinou, Green: "Breaking the mitochondrial barrier." in: Nature reviews. Molecular cell biology, Vol. 2, Issue 1, pp. 63-7, 2001 (PubMed).

Validation Images
Did you look for something else?
back to top