COMP antibody (N-Term)

Catalog No. ABIN5514649

Product Details anti-COMP Antibody

Target: COMP (Cartilage Oligomeric Matrix Protein (COMP))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Pig, Dog, Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COMP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CVLLLTLAAL GASGQGQSPL GSDLGPQMLR ELQETNAALQ DVRELLRQQV

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against COMP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human COMP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COMP

Target: COMP (Cartilage Oligomeric Matrix Protein (COMP))

Alternative Name: COMP (COMP Products)

Synonyms: COMP antibody, EDM1 antibody, EPD1 antibody, MED antibody, PSACH antibody, THBS5 antibody, TSP5 antibody, cartilage oligomeric matrix protein antibody, COMP antibody, sce3551 antibody, CJA_1292 antibody, Comp antibody

Background: The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).

Alias Symbols: COMP,

Protein Interaction Partner: OTX1, FN1, COL9A1, COL2A1,

Protein Size: 757

Gene ID: 1311

NCBI Accession: NP_000086

UniProt: P49747