MESDC2 antibody (Middle Region)

Catalog No. ABIN5514967

Product Details anti-MESDC2 Antibody

Target: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MESDC2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LPPPGSCAAE GSPGTPDEST PPPRKKKKDI RDYNDADMAR LLEQWEKDDD

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MESDC2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MESDC2

Target: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Alternative Name: MESDC2 (MESDC2 Products)

Synonyms: MGC115616 antibody, MESDC2 antibody, BOCA antibody, MESD antibody, 2210015O11Rik antibody, AW537813 antibody, mKIAA0081 antibody, mesd antibody, msd antibody, zgc:158636 antibody, mesoderm development LRP chaperone antibody, mesoderm development LRP chaperone L homeolog antibody, mesoderm development candidate 2 antibody, MESD antibody, mesd.L antibody, CpipJ_CPIJ010816 antibody, Tsp_04045 antibody, mesd antibody, Mesd antibody, MESDC2 antibody

Background: Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.

Alias Symbols: BOCA, MESD

Protein Size: 234

Gene ID: 23184

NCBI Accession: NM_015154, NP_055969

UniProt: Q14696