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MESDC2 antibody (Middle Region)
MESDC2
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MESDC2 Antibody
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Target
See all MESDC2 Antibodies
MESDC2
(Mesoderm Development Candidate 2 (MESDC2))
Binding Specificity
All epitopes for MESDC2 antibodies
Middle Region
Reactivity
All reactivities for MESDC2 antibodies
Human
Host
All hosts for MESDC2 antibodies
Rabbit
Clonality
All clonalities for MESDC2 antibodies
Polyclonal
Conjugate
All conjugates for MESDC2 antibodies
This MESDC2 antibody is un-conjugated
Application
All applications for MESDC2 antibodies
Western Blotting (WB)
Sequence
LPPPGSCAAE GSPGTPDEST PPPRKKKKDI RDYNDADMAR LLEQWEKDDD
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human MESDC2
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for MESDC2
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Target
MESDC2
(Mesoderm Development Candidate 2 (MESDC2))
Alternative Name
MESDC2 (MESDC2 Products )
Synonyms
MGC115616 antibody, MESDC2 antibody, BOCA antibody, MESD antibody, 2210015O11Rik antibody, AW537813 antibody, mKIAA0081 antibody, mesd antibody, msd antibody, zgc:158636 antibody, mesoderm development LRP chaperone antibody, mesoderm development LRP chaperone L homeolog antibody, mesoderm development candidate 2 antibody, MESD antibody, mesd.L antibody, CpipJ_CPIJ010816 antibody, Tsp_04045 antibody, mesd antibody, Mesd antibody, MESDC2 antibody
Background
Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Alias Symbols: BOCA, MESD Protein Size: 234
Gene ID
23184
NCBI Accession
NM_015154 , NP_055969
UniProt
Q14696
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