VMP1 antibody (Middle Region)

Catalog No. ABIN5515450

Product Details anti-VMP1 Antibody

Target: VMP1 (Vacuole Membrane Protein 1 (VMP1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VMP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SIISKVRIEA CMWGIGTAIG ELPPYFMARA ARLSGAEPDD EEYQEFEEML

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 80%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against VMP1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human VMP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VMP1

Target: VMP1 (Vacuole Membrane Protein 1 (VMP1))

Alternative Name: VMP1 (VMP1 Products)

Synonyms: 3110098I04Rik antibody, 4930579A11Rik antibody, AI787464 antibody, Tango5 antibody, Tmem49 antibody, ni-2 antibody, EPG3 antibody, TANGO5 antibody, TMEM49 antibody, DDBDRAFT_0186376 antibody, DDBDRAFT_0234044 antibody, DDB_0186376 antibody, DDB_0234044 antibody, epg3 antibody, tmem49 antibody, wu:fb05d08 antibody, wu:fb92g08 antibody, zgc:77153 antibody, vacuole membrane protein 1 antibody, TMEM49 family protein antibody, vacuole membrane protein 1 L homeolog antibody, Vmp1 antibody, VMP1 antibody, LOC551036 antibody, vmp1 antibody, vmp1.L antibody

Background: VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. It may be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. And it plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). It involved in cell-cell adhesion. It plays an essential role in formation of cell junctions.

Alias Symbols: VMP1, TDC1, TMEM49, HSPC292,

Protein Interaction Partner: TJP1, UBC, ELAVL1, HGS,

Protein Size: 406

Gene ID: 81671

NCBI Accession: NP_112200

UniProt: Q96GC9