KCNA2 antibody (N-Term)

Catalog No. ABIN5515522

Product Details anti-KCNA2 Antibody

Target: KCNA2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 2 (KCNA2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNA2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AAALPGHPQD TYDPEADHEC CERVVINISG LRFETQLKTL AQFPETLLGD

Characteristics: This is a rabbit polyclonal antibody against KCNA2. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human KCNA2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCNA2

Target: KCNA2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 2 (KCNA2))

Alternative Name: KCNA2 (KCNA2 Products)

Synonyms: KCNA2 antibody, kcna2 antibody, HBK5 antibody, HK4 antibody, HUKIV antibody, KV1.2 antibody, MK2 antibody, NGK1 antibody, RBK2 antibody, Akr6a4 antibody, ENSMUSG00000074335 antibody, Gm10672 antibody, Kca1-2 antibody, Kv1.2 antibody, Mk-2 antibody, BK2 antibody, XSha2 antibody, k(v)1.2 antibody, kcna2-a antibody, kv1.2 antibody, potassium voltage-gated channel subfamily A member 2 antibody, potassium channel, voltage gated shaker related subfamily A, member 1 antibody, potassium voltage-gated channel, shaker-related subfamily, member 2 antibody, potassium channel, voltage gated shaker related subfamily A, member 2 S homeolog antibody, KCNA2 antibody, kcna1 antibody, Kcna2 antibody, LOC100537815 antibody, kcna2.S antibody

Background: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.

Protein Size: 499

Gene ID: 3737

NCBI Accession: NP_004965

UniProt: P16389