AEN antibody (N-Term)

Catalog No. ABIN5515721

Product Details anti-AEN Antibody

Target: AEN (Apoptosis Enhancing Nuclease (AEN))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AEN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: REAPESAQCL CPSLTIPNAK DVLRKRHKRR SRQHQRFMAR KALLQEQGLL

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AEN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AEN

Target: AEN (Apoptosis Enhancing Nuclease (AEN))

Alternative Name: AEN (AEN Products)

Synonyms: AEN antibody, ISG20L1 antibody, xaen antibody, isg20l1 antibody, MGC147218 antibody, pp12744 antibody, 2700083B06Rik antibody, Isg20l1 antibody, RGD1305051 antibody, apoptosis enhancing nuclease antibody, apoptosis enhancing nuclease L homeolog antibody, AEN antibody, aen.L antibody, aen antibody, Aen antibody

Background: Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.

Alias Symbols: ISG20L1, pp12744

Protein Size: 325

Gene ID: 64782

NCBI Accession: NM_022767, NP_073604

UniProt: Q8WTP8