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AIPL1 antibody (C-Term)
AIPL1
Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Rabbit
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-AIPL1 Antibody
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Target
See all AIPL1 Antibodies
AIPL1
(Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1))
Binding Specificity
All epitopes for AIPL1 antibodies
C-Term
Reactivity
Human, Mouse, Rat, Cow, Horse, Pig, Rabbit
Host
All hosts for AIPL1 antibodies
Rabbit
Clonality
All clonalities for AIPL1 antibodies
Polyclonal
Conjugate
All conjugates for AIPL1 antibodies
This AIPL1 antibody is un-conjugated
Application
All applications for AIPL1 antibodies
Western Blotting (WB)
Sequence
DLDELQKEPQ PLVFVIELLQ VDAPSDYQRE TWNLSNHEKM KAVPVLHGEG
Predicted Reactivity
Cow: 79%, Horse: 86%, Human: 100%, Mouse: 77%, Pig: 86%, Rabbit: 79%, Rat: 77%
Characteristics
This is a rabbit polyclonal antibody against AIPL1. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of human AIPL1
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for AIPL1
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Target
AIPL1
(Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1))
Alternative Name
AIPL1 (AIPL1 Products )
Synonyms
AIPL1 antibody, lca4 antibody, aipl2 antibody, AIPL2 antibody, LCA4 antibody, A930007I01Rik antibody, aryl hydrocarbon receptor interacting protein like 1 antibody, aryl hydrocarbon receptor-interacting protein-like 1 antibody, AIPL1 antibody, aipl1 antibody, Aipl1 antibody
Background
Leber congenital amaurosis (LCA) is the most severe inherited retinopathy with the earliest age of onset and accounts for at least 5 % of all inherited retinal diseases. Affected individuals are diagnosed at birth or in the first few months of life with nystagmus, severely impaired vision or blindness and an abnormal or flat electroretinogram. The photoreceptor/pineal-expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, is located within the LCA4 candidate region. The encoded protein contains three tetratricopeptide motifs, consistent with chaperone or nuclear transport activity. Mutations in this gene may cause approximately 20 % of recessive LCA. Alternative splicing results in multiple transcript variants. Alias Symbols: LCA4, AIPL2 Protein Size: 270
Gene ID
23746
NCBI Accession
NM_001285403 , NP_001272332
UniProt
F1T0C4
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