DEFA5 antibody (N-Term)

Catalog No. ABIN5515995

Product Details anti-DEFA5 Antibody

Target: DEFA5 (Defensin, alpha 5, Paneth Cell-Specific (DEFA5))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEFA5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QAQAESLQER ADEATTQKQS GEDNQDLAIS FAGNGLSALR TSGSQARATC

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against DEF5. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human DEF5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DEFA5

Target: DEFA5 (Defensin, alpha 5, Paneth Cell-Specific (DEFA5))

Alternative Name: DEF5 (DEFA5 Products)

Synonyms: DEF5 antibody, HD-5 antibody, Defa29 antibody, Defcr29 antibody, Defcr5 antibody, DEFA1 antibody, DEFA5 antibody, Defa antibody, defensin alpha 5 antibody, defensin, alpha, 5 antibody, defensin, alpha 5, Paneth cell-specific antibody, alpha-defensin 1A antibody, DEFA5 antibody, Defa5 antibody, MNP1A antibody

Background: Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.

Alias Symbols: DEFA5, DEF5,

Protein Interaction Partner: DTX1, PRSS1,

Protein Size: 94

Gene ID: 1670

NCBI Accession: NP_066290

UniProt: Q01523