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DEFA5 antibody (N-Term)
DEFA5
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DEFA5 Antibody
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Target
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DEFA5
(Defensin, alpha 5, Paneth Cell-Specific (DEFA5))
Binding Specificity
All epitopes for DEFA5 antibodies
N-Term
Reactivity
All reactivities for DEFA5 antibodies
Human
Host
All hosts for DEFA5 antibodies
Rabbit
Clonality
All clonalities for DEFA5 antibodies
Polyclonal
Conjugate
All conjugates for DEFA5 antibodies
This DEFA5 antibody is un-conjugated
Application
All applications for DEFA5 antibodies
Western Blotting (WB)
Sequence
QAQAESLQER ADEATTQKQS GEDNQDLAIS FAGNGLSALR TSGSQARATC
Predicted Reactivity
Human: 100%
Characteristics
This is a rabbit polyclonal antibody against DEF5. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human DEF5
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for DEFA5
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Target
DEFA5
(Defensin, alpha 5, Paneth Cell-Specific (DEFA5))
Alternative Name
DEF5 (DEFA5 Products )
Synonyms
DEF5 antibody, HD-5 antibody, Defa29 antibody, Defcr29 antibody, Defcr5 antibody, DEFA1 antibody, DEFA5 antibody, Defa antibody, defensin alpha 5 antibody, defensin, alpha, 5 antibody, defensin, alpha 5, Paneth cell-specific antibody, alpha-defensin 1A antibody, DEFA5 antibody, Defa5 antibody, MNP1A antibody
Background
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum. Alias Symbols: DEFA5, DEF5, Protein Interaction Partner: DTX1, PRSS1, Protein Size: 94
Gene ID
1670
NCBI Accession
NP_066290
UniProt
Q01523
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