GUCA2B antibody (Middle Region)

Catalog No. ABIN5516344

Product Details anti-GUCA2B Antibody

Target: GUCA2B (Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCA2B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MKKLSDLEAQ WAPSPRLQAQ SLLPAVCHHP ALPQDLQPVC ASQEASSIFK

Characteristics: This is a rabbit polyclonal antibody against GUC2B. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen for Anti-GUCA2B antibody is: synthetic peptide directed towards the middle region of Human GUC2B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GUCA2B

Target: GUCA2B (Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B))

Alternative Name: GUCA2B (GUCA2B Products)

Background: This gene encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues.

Alias Symbols: UGN, GCAP-II,

Protein Size: 112

Gene ID: 2981

NCBI Accession: NP_009033

UniProt: Q16661