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CBX7 antibody (C-Term)

CBX7 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5516358
  • Target See all CBX7 Antibodies
    CBX7 (Chromobox Homolog 7 (CBX7))
    Binding Specificity
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 37
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 29
    • 7
    • 1
    Rabbit
    Clonality
    • 24
    • 13
    Polyclonal
    Conjugate
    • 23
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CBX7 antibody is un-conjugated
    Application
    • 21
    • 10
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LSRKKFPPRG PNLESHSHRR ELFLQEPPAP DVLQAAGEWE PAAQPPEEEA
    Characteristics
    This is a rabbit polyclonal antibody against CBX7. It was validated on Western Blot.
    Purification
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human CBX7
    Top Product
    Discover our top product CBX7 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CBX7 (Chromobox Homolog 7 (CBX7))
    Alternative Name
    CBX7 (CBX7 Products)
    Synonyms
    1600014J01Rik antibody, AI851678 antibody, D15Ertd417e antibody, zgc:110152 antibody, chromobox 7 antibody, chromobox homolog 7a antibody, CBX7 antibody, Cbx7 antibody, cbx7a antibody
    Background
    CBX7 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.

    Protein Size: 251
    Gene ID
    23492
    NCBI Accession
    NP_783640
    UniProt
    O95931
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