KCNE2 antibody (Middle Region)

Catalog No. ABIN5516924

Product Details anti-KCNE2 Antibody

Target: KCNE2 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 2 (KCNE2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNE2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MVMIGMFSFI IVAILVSTVK SKRREHSNDP YHQYIVEDWQ EKYKSQILNL

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KCNE2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCNE2

Target: KCNE2 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 2 (KCNE2))

Alternative Name: KCNE2 (KCNE2 Products)

Synonyms: ATFB4 antibody, LQT5 antibody, LQT6 antibody, MIRP1 antibody, Mirp1 antibody, MiRP1 antibody, 2200002I16Rik antibody, AW048273 antibody, potassium voltage-gated channel subfamily E regulatory subunit 2 antibody, potassium voltage-gated channel, Isk-related subfamily, gene 2 antibody, KCNE2 antibody, Kcne2 antibody

Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia.

Alias Symbols: LQT5, LQT6, ATFB4, MIRP1

Protein Size: 123

Gene ID: 9992

NCBI Accession: NM_172201, NP_751951

UniProt: Q9Y6J6