PDE6D antibody (N-Term)

Catalog No. ABIN5517276

Product Details anti-PDE6D Antibody

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Pig, Rabbit, Zebrafish (Danio rerio), Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE6D antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PDE6D. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDE6D

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDE6D

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Alternative Name: PDE6D (PDE6D Products)

Synonyms: zgc:92605 antibody, PDE6D antibody, PDED antibody, AI841218 antibody, PrBP/delta antibody, phosphodiesterase 6D antibody, phosphodiesterase 6D, cGMP-specific, rod, delta antibody, Pde6d antibody, PDE6D antibody, pde6d antibody

Background: PDE6D acts as a GTP specific dissociation inhibitor (GDI). It increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. It stabilizes ARL3-GTP by decreasing the nucleotide dissociation.

Alias Symbols: PDE6D, PDED,

Protein Interaction Partner: ARL16, ARL2, UBC, PTGIR, COPS5, CUL1, FAM219A, ARL15, RND1, GRK7, RAD23A, ARL3, CETN3, RAB13, RAB18, RHEB, RPGR, HRAS, GRK1, RAP2B, RAP1A, RHOA, RHOB, RAB8A, GNAI1, RASA1, CDC42,

Protein Size: 150

Gene ID: 5147

NCBI Accession: NP_002592

UniProt: O43924