SCYL2 antibody (C-Term)

Catalog No. ABIN5517315

Product Details anti-SCYL2 Antibody

Target: SCYL2 (SCY1-Like 2 (SCYL2))

Binding Specificity: C-Term

Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCYL2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DLLTGSESEN KEDGLQNKHK RASLTLEEKQ KLAKEQEQAQ KLKSQQPLKP

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SCYL2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SCYL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SCYL2

Target: SCYL2 (SCY1-Like 2 (SCYL2))

Alternative Name: SCYL2 (SCYL2 Products)

Synonyms: RGD1305665 antibody, CVAK104 antibody, AU015688 antibody, AW536445 antibody, BC030932 antibody, D10Ertd802e antibody, SCY1 like pseudokinase 2 antibody, SCY1-like protein 2 antibody, SCY1-like 2 (S. cerevisiae) antibody, Scyl2 antibody, SCYL2 antibody, LOC452160 antibody

Background: SCYL2 is a component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, it is a probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L- lysine. According to PubMed:16914521, it has no detectable kinase activity in vitro. It may regulate clathrin-dependent trafficking between the TGN and/or the endosomal system.

Alias Symbols: SCYL2, CVAK104, KIAA1360,

Protein Interaction Partner: RAPGEF2, SUMO2, SUMO3, FBXO6, SOX2, Dlg4, ZFYVE9, EIF4A3, MAGOH, ESR1, SPEN, ARRB2, ARRB1, UBC, NOP56, GTF3A, CLTC,

Protein Size: 929

Gene ID: 55681

NCBI Accession: XP_005269075

UniProt: Q6P3W7