RNASEH2C antibody (Middle Region)

Catalog No. ABIN5517614

Product Details anti-RNASEH2C Antibody

Target: RNASEH2C (Ribonuclease H2, Subunit C (RNASEH2C))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASEH2C antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VAVPPGLVGY VMVTEEKKVS MGKPDPLRDS GTDDQEEEPL ERDFDRFIGA

Characteristics: This is a rabbit polyclonal antibody against RNASEH2C. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human RNASEH2C

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RNASEH2C

Target: RNASEH2C (Ribonuclease H2, Subunit C (RNASEH2C))

Alternative Name: RNASEH2C (RNASEH2C Products)

Synonyms: AGS3 antibody, AYP1 antibody, 1500026D16Rik antibody, ribonuclease H2 subunit C antibody, ribonuclease H2, subunit C antibody, RNASEH2C antibody, Rnaseh2c antibody

Background: This gene encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes. Mutations in this gene cause Aicardi-Goutieres syndrome-3, a disease that causes severe neurologic dysfunction. A pseudogene for this gene has been identified on chromosome Y, near the sex determining region Y (SRY) gene.

Alias Symbols: RNASEH2C, AYP1,

Protein Interaction Partner: UBC, RNASEH2B, RNASEH2A, OXSR1,

Protein Size: 164

Gene ID: 84153

NCBI Accession: NP_115569

UniProt: Q8TDP1