AQP6 antibody (C-Term)

Catalog No. ABIN5518807

Product Details anti-AQP6 Antibody

Target: AQP6 (Aquaporin 6, Kidney Specific (AQP6))

Binding Specificity: AA 238-271, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AQP6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Aquaporin-6(AQP6) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequence: DTKTLAQRLA ILTGTVEVGT GAGAGAEPLK KESQ

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Aquaporin-6(AQP6) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: aquaporin 6
Protein Name: Aquaporin-6

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 6 (238-271aa DTKTLAQRLAILTGTVEVGTGAGAGAEPLKKESQ), different from the related mouse and rat sequences by fourteen amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for AQP6

Target: AQP6 (Aquaporin 6, Kidney Specific (AQP6))

Alternative Name: AQP6 (AQP6 Products)

Synonyms: AI790337 antibody, AQP2L antibody, KID antibody, aquaporin 6 antibody, Aqp6 antibody, AQP6 antibody

Background: Aquaporin 6, kidney specific is a protein in humans that is encoded by the AQP6 gene. The aquaporins (AQPs) are a family of water-transporting proteins that facilitate osmotically driven water movement across cell plasma membranes. Among the seven human aquaporins cloned to date (AQPs 0-6), genes encoding the four most closely related aquaporins (AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. Unlike other aquaporins, AQP6 functions not as a water channel but as an anion-selective channel. Single-channel analyses have shown AQP6 to flicker rapidly between closed and open status.

Synonyms: Aquaporin-6 | AQP-6 | Aquaporin-2-like | Kidney-specific aquaporin | hKID | AQP6 | AQP2L | Q13520

Gene ID: 363

UniProt: Q13520