CA4 antibody (AA 19-284)

Catalog No. ABIN5518815

Product Details anti-CA4 Antibody

Target: CA4 (Carbonic Anhydrase IV (CA4))

Binding Specificity: AA 19-284

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA4 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Carbonic anhydrase 4(CA4) detection. Tested with WB in Human,Mouse,Rat.

Cross-Reactivity (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Carbonic anhydrase 4(CA4) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: carbonic anhydrase 4
Protein Name: Carbonic anhydrase 4

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CA IV recombinant protein (Position: A19-S284). Human CA IV shares 55.5% and 58.9% amino acid (aa) sequence identity with mouse and rat CA IV, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for CA4

Target: CA4 (Carbonic Anhydrase IV (CA4))

Alternative Name: CA4 (CA4 Products)

Synonyms: CAIV antibody, Car4 antibody, RP17 antibody, AW456718 antibody, Ca4 antibody, ca4 antibody, caiv antibody, car4 antibody, rp17 antibody, CA4 antibody, zgc:171842 antibody, carbonic anhydrase 4 antibody, carbonic anhydrase 4 S homeolog antibody, carbonic anhydrase IV a antibody, CA4 antibody, Car4 antibody, ca4 antibody, ca4.S antibody, Ca4 antibody, ca4a antibody

Background: Carbonic anhydrase 4 is an enzyme that in humans is encoded by the CA4 gene. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.

Synonyms: CA IV | CAIV | CA4 | Car4 | RP17 | P22748

Gene ID: 762

UniProt: P22748