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RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) (AA 1648-1708) antibody

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Antigen
Alternatives
Epitope
AA 1648-1708
(27), (26), (13), (13), (5), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Reactivity
Human
(145), (46), (12), (5), (5), (1), (1)
Host
Rabbit
(93), (34), (20)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(96), (75), (63), (29), (21), (13), (12), (8), (7), (6), (2), (1), (1), (1)
Pubmed 4 references available
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Quantity 0.1 mL
Shipping to United States ( )
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Immunogen Synthetic peptide corresponding to a region within amino acids 1648 and 1708 of RICTOR
Isotype IgG
Predicted Reactivity Bovine (90%)
Purification Purified by antigen-affinity chromatography..
Alternative Name RICTOR (RICTOR Antibody Abstract)
Background RICTOR and MTOR (FRAP1, MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM]
Synonyms: DKFZp686B11164 antibody, KIAA1999 antibody, MGC39830 antibody, PIA antibody, mAVO3 antibody, RICTOR antibody, hAVO3 antibody, AVO3 homolog antibody, pianissimo antibody, rapamycin-insensitive companion of mTOR antibody, TORC2-specific protein AVO3 antibody, "RPTOR independent companion of MTOR, complex 2 antibody"
Molecular Weight 192 kDa
UniProt Q6R327
Research Area Signaling
Pathways Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Comment

Positive Controls: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Supplier Images
Immunofluorescence (IF) image for anti-RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) (AA 1648-1708) antibody (ABIN552595) anti-RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) (AA 1648-1708) antibody
Western Blotting (WB) image for anti-RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) (AA 1648-1708) antibody (ABIN552595) anti-RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) (AA 1648-1708) antibody (Image 2)
Product cited in: Taipale, Beachy: "The Hedgehog and Wnt signalling pathways in cancer." in: Nature, Vol. 411, Issue 6835, pp. 349-54, 2001 (PubMed).

Polakis: "Wnt signaling and cancer." in: Genes & development, Vol. 14, Issue 15, pp. 1837-51, 2000 (PubMed).

McWhirter, Neuteboom, Wancewicz et al.: "Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 20, pp. 11464-9, 1999 (PubMed).

Cadigan, Nusse: "Wnt signaling: a common theme in animal development." in: Genes & development, Vol. 11, Issue 24, pp. 3286-305, 1998 (PubMed).

Catalog No. ABIN552595

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