Triosephosphate Isomerase 1 (TPI1) (AA 187-249) antibody

Details for Product No. ABIN552596
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Antigen
Synonyms CG2171, Dmel\\CG2171, ND14, TPI, TPIS, sgk, tpi, wstd, TPI1, TIM, tpi1, GB17473, AI255506, Tpi, Tpi-1
Epitope
AA 187-249
(7), (7), (6), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(39), (13), (6), (5), (5), (3), (3), (3), (1)
Host
Rabbit
(29), (12), (5), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (1), (1), (1), (1), (1)
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(50), (24), (16), (10), (7), (7), (7), (4), (3), (3), (2), (1), (1), (1), (1)
Pubmed 5 references available
Quantity 0.1 mL
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Catalog No. ABIN552596
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Immunogen Synthetic peptide corresponding to a region within amino acids 187 and 249 of Triosephosphate isomerase
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Predicted Reactivity Yeast (83%), Xenopus Tropicalis (92%), Dog (100%), Chicken (92%), Chimpanzee (100%), Bovine (100%)
Purification Purified by antigen-affinity chromatography..
Alternative Name Triosephosphate isomerase (TPI1)
Background This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
Synonyms: MGC88108 antibody, TPI antibody, TPI1 antibody, triose-phosphate isomerase antibody, triosephosphate isomerase antibody, triosephosphate isomerase 1 antibody
Molecular Weight 31 kDa
UniProt P60174
Comment

Positive Controls: A431 , H1299 , Neuro2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12 , PC-12 , Rat2

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Lamarre, Talbot, Leduc et al.: "Production and characterization of monoclonal antibodies specific for the functional domains of poly(ADP-ribose) polymerase." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 64, Issue 4, pp. 368-76, 1986 (PubMed).

Lamarre, Talbot, de Murcia et al.: "Structural and functional analysis of poly(ADP ribose) polymerase: an immunological study." in: Biochimica et biophysica acta, Vol. 950, Issue 2, pp. 147-60, 1988 (PubMed).

Tewari, Quan, ORourke et al.: "Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase." in: Cell, Vol. 81, Issue 5, pp. 801-9, 1995 (PubMed).

Patel, Gores, Kaufmann: "The role of proteases during apoptosis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 10, Issue 5, pp. 587-97, 1996 (PubMed).

DAmours, Desnoyers, DSilva et al.: "Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions." in: The Biochemical journal, Vol. 342 ( Pt 2), Issue 5691, pp. 249-68, 1999 (PubMed).

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