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serine/threonine Kinase 17b (STK17B) (AA 309-372) antibody

Details for Product No. ABIN552782, Supplier: Login to see
Antigen
  • zgc:65989
  • STK17B
  • DRAK2
  • Drak2
  • 3110009A03Rik
  • AI120141
Epitope
AA 309-372
37
16
15
11
3
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
105
26
22
3
2
1
1
Host
Rabbit
83
18
6
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
ELISA
80
39
18
15
11
10
9
3
2
2
2
Supplier
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Immunogen Synthetic peptide corresponding to a region within amino acids 309 and 372 of DRAK2
Isotype IgG
Predicted Reactivity Bovine (92%)
Characteristics Cellular Localization: Nucleus
Purification Purified by antigen-affinity chromatography..
Alternative Name STK17B / DRAK2 (STK17B Antibody Abstract)
Background Acts as a positive regulator of apoptosis.
Synonyms: DRAK2 antibody, STK17B antibody, DAP kinase-related apoptosis-inducing protein kinase 2 antibody, serine/threonine-protein kinase 17B antibody, death-associated protein kinase-related 2 antibody, serine/threonine kinase 17b antibody
Molecular Weight 42 kDa
UniProt O94768
Pathways
Comment

Positive Controls: Synthetic peptide: 1:8,000

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Krajewska, Krajewski, Banares et al.: "Elevated expression of inhibitor of apoptosis proteins in prostate cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 9, Issue 13, pp. 4914-25, 2003 (PubMed).

Salvesen, Duckett: "IAP proteins: blocking the road to death's door." in: Nature reviews. Molecular cell biology, Vol. 3, Issue 6, pp. 401-10, 2002 (PubMed).

Goyal: "Cell death inhibition: keeping caspases in check." in: Cell, Vol. 104, Issue 6, pp. 805-8, 2001 (PubMed).

Roy, Mahadevan, McLean et al.: "The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy." in: Cell, Vol. 80, Issue 1, pp. 167-78, 1995 (PubMed).

Background publications Deveraux, Reed: "IAP family proteins--suppressors of apoptosis." in: Genes & development, Vol. 13, Issue 3, pp. 239-52, 1999 (PubMed).

Roy, Deveraux, Takahashi et al.: "The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases." in: The EMBO journal, Vol. 16, Issue 23, pp. 6914-25, 1998 (PubMed).

Rothe, Pan, Henzel et al.: "The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins." in: Cell, Vol. 83, Issue 7, pp. 1243-52, 1996 (PubMed).