serine/threonine Kinase 17b (STK17B) (AA 309-372) antibody

Details for Product No. ABIN552782
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Antigen
Synonyms zgc:65989, STK17B, DRAK2, Drak2, 3110009A03Rik, AI120141
Epitope
AA 309-372
(37), (15), (12), (10), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(105), (25), (23), (1)
Host
Rabbit
(82), (21), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA
(81), (38), (19), (17), (10), (9), (8), (3), (3), (2), (2), (2), (1)
Pubmed 7 references available
Quantity 0.1 mL
Shipping to United States (Change)
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The Independent Validation Initiative strives to provide you with high quality data. Find out more

Immunogen Synthetic peptide corresponding to a region within amino acids 309 and 372 of DRAK2
Isotype IgG
Predicted Reactivity Bovine (92%)
Characteristics Cellular Localization: Nucleus
Purification Purified by antigen-affinity chromatography..
Alternative Name STK17B / DRAK2 (STK17B Antibody Abstract)
Background Acts as a positive regulator of apoptosis.
Synonyms: DRAK2 antibody, STK17B antibody, DAP kinase-related apoptosis-inducing protein kinase 2 antibody, serine/threonine-protein kinase 17B antibody, death-associated protein kinase-related 2 antibody, serine/threonine kinase 17b antibody
Molecular Weight 42 kDa
UniProt O94768
Comment

Positive Controls: Synthetic peptide: 1:8,000

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Krajewska, Krajewski, Banares et al.: "Elevated expression of inhibitor of apoptosis proteins in prostate cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 9, Issue 13, pp. 4914-25, 2003 (PubMed).

Salvesen, Duckett: "IAP proteins: blocking the road to death's door." in: Nature reviews. Molecular cell biology, Vol. 3, Issue 6, pp. 401-10, 2002 (PubMed).

Goyal: "Cell death inhibition: keeping caspases in check." in: Cell, Vol. 104, Issue 6, pp. 805-8, 2001 (PubMed).

Deveraux, Reed: "IAP family proteins--suppressors of apoptosis." in: Genes & development, Vol. 13, Issue 3, pp. 239-52, 1999 (PubMed).

Roy, Deveraux, Takahashi et al.: "The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases." in: The EMBO journal, Vol. 16, Issue 23, pp. 6914-25, 1998 (PubMed).

Rothe, Pan, Henzel et al.: "The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins." in: Cell, Vol. 83, Issue 7, pp. 1243-52, 1996 (PubMed).

Roy, Mahadevan, McLean et al.: "The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy." in: Cell, Vol. 80, Issue 1, pp. 167-78, 1995 (PubMed).

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Catalog No. ABIN552782
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