NUP85 antibody (AA 163-195)

Catalog No. ABIN5531722

Product Details anti-NUP85 Antibody

Target: NUP85 (Nucleoporin 85kDa (NUP85))

Binding Specificity: AA 163-195

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP85 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NUP85 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 163-195 amino acids from human NUP85.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NUP85

Target: NUP85 (Nucleoporin 85kDa (NUP85))

Alternative Name: NUP85 (NUP85 Products)

Synonyms: Pcnt1 antibody, frount antibody, pcnt1 antibody, zgc:100943 antibody, Nup75 antibody, nucleoporin 85kDa L homeolog antibody, nucleoporin 85kDa antibody, nucleoporin 85 antibody, nup85.L antibody, nup85 antibody, NUP85 antibody, Nup85 antibody

Background: Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2- activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl- inositol 3-kinase-Rac-lammellipodium protrusion cascade.

Molecular Weight: 75 kDa

Gene ID: 79902

UniProt: Q9BW27