URI1 antibody (C-Term)

Catalog No. ABIN5532036

Product Details anti-URI1 Antibody

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Binding Specificity: AA 347-376, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This URI1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This RMP (URI) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 347-376 amino acids from the C-terminal region of human RMP (URI).

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for URI1

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Alternative Name: RMP (URI1 Products)

Synonyms: c19orf2 antibody, C19orf2 antibody, NNX3 antibody, PPP1R19 antibody, RMP antibody, URI antibody, URI1 prefoldin-like chaperone L homeolog antibody, URI1, prefoldin like chaperone antibody, uri1.L antibody, URI1 antibody

Background: The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 60 kDa

Gene ID: 8725

UniProt: O94763