FRAT1 antibody (AA 99-128)

Catalog No. ABIN5534285

Product Details anti-FRAT1 Antibody

Target: FRAT1 (Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))

Binding Specificity: AA 99-128

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This FRAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-128 amino acids from the Central region of human FRAT1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for FRAT1

Target: FRAT1 (Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))

Alternative Name: FRAT1 (FRAT1 Products)

Synonyms: FRAT1 antibody, frat1 antibody, AW060382 antibody, gbp antibody, FRAT1, WNT signaling pathway regulator antibody, GSK-3 binding protein FRAT1 antibody, frequently rearranged in advanced T cell lymphomas antibody, frequently rearranged in advanced T-cell lymphomas antibody, frequently rearranged in advanced T-cell lymphomas 1 S homeolog antibody, FRAT1 antibody, frat1 antibody, Frat1 antibody, frat1.S antibody

Background: FRAT1 belongs to the GSK-3-binding protein family. It may function in tumor progression and in lymphomagenesis. It positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. It may play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.

Molecular Weight: 29 kDa

Gene ID: 10023

UniProt: Q92837