COX7A2L antibody (AA 37-65)

Catalog No. ABIN5536882

Product Details anti-COX7A2L Antibody

Target: COX7A2L (Cytochrome C Oxidase Subunit VIIa Polypeptide 2 Like (COX7A2L))

Binding Specificity: AA 37-65

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX7A2L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This COX7A2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the Central region of human COX7A2L.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for COX7A2L

Target: COX7A2L (Cytochrome C Oxidase Subunit VIIa Polypeptide 2 Like (COX7A2L))

Alternative Name: COX7A2L (COX7A2L Products)

Synonyms: COX7AR antibody, COX7RP antibody, EB1 antibody, SIG81 antibody, SIG-81 antibody, Silg81 antibody, cytochrome c oxidase subunit 7A2 like antibody, cytochrome c oxidase subunit VIIa polypeptide 2-like antibody, COX7A2L antibody, Cox7a2l antibody

Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.

Molecular Weight: 13 kDa

Gene ID: 9167

UniProt: O14548