SERPINB11 antibody (AA 170-196)

Catalog No. ABIN5538461

Product Details anti-SERPINB11 Antibody

Target: SERPINB11 (Serine (Or Cysteine) Peptidase Inhibitor, Clade B (Ovalbumin), Member 11 (SERPINB11))

Binding Specificity: AA 170-196

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINB11 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SERPINB11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-196 amino acids from the Central region of human SERPINB11.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SERPINB11

Target: SERPINB11 (Serine (Or Cysteine) Peptidase Inhibitor, Clade B (Ovalbumin), Member 11 (SERPINB11))

Alternative Name: SERPINB11 (SERPINB11 Products)

Synonyms: 2310046M08Rik antibody, AU015399 antibody, EPIPIN antibody, SERPIN11 antibody, serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11 antibody, serpin family B member 11 (gene/pseudogene) antibody, Serpinb11 antibody, SERPINB11 antibody

Background: SerpinB11 is a serine proteinase inhibitor of the ovalbumin-like B clade of serpins. It was first discovered in human lung and prostate. Little is known about SerpinB11 tissue distribution and function. Splice variants of 305, 278 and 190 amino acids have been reported, with predicted masses of 33.97, 31.6 and 21.1 kDa respectively, and pIs of 8.11, 9.03 and 6.07 respectively. The 305 and 190 amino acid forms share the same aminoterminus as the 392 amino acid form. The 305 amino acid form has a deletion in residues 120-206, of the 392 amino acid form. The 190 amino acid form has a deletion in residues 57-259 relative to the long form. The 278 amino acid form starts at the third methionine, relative to the long form. All four forms contain the reactive center loop of the long form, but it is unknown if the shorter forms are active serpins. The predicted isoelectric points of SerpinB11 are significantly more basic than the other B clade serpins, and suggest a different localization or function for this serpin.

Molecular Weight: 44 kDa

Gene ID: 89778

UniProt: Q96P15