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phosphofructokinase, Platelet (PFKP) (AA 392-784) antibody

Details for Product No. ABIN554095
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Antigen
Synonyms pfk, pfk-c, pfkf, PFKP, PFK-C, PFKF, 1200015H23Rik, 9330125N24Rik, PFKM
Epitope
AA 392-784
(13), (7), (6), (4), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(57), (10), (10), (3)
Host
Rabbit
(37), (20)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(50), (26), (24), (17), (12), (12), (5), (4), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mL
Shipping to United States (Change)
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Catalog No. ABIN554095
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Immunogen Recombinant fragment corresponding to a region within amino acids 392 and 784 of PFK (platelet)
Isotype IgG
Cross-Reactivity Mouse (Murine)
Predicted Reactivity Rabbit (93%), Rat (88%), Bovine (90%)
Purification Purified by antigen-affinity chromatography..
Alternative Name PFKP
Background The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM, MIM 610681) and liver (PFKL, MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.[supplied by OMIM]
Synonyms: FLJ40226 antibody, PFK-C antibody, PFKF antibody, PFKP antibody, phosphohexokinase antibody, phosphofructokinase 1 antibody, phosphofructo-1-kinase isozyme C antibody, "Phosphofructokinase, platelet type antibody", 6-phosphofructokinase type C antibody, "6-phosphofructokinase, platelet type antibody", "phosphofructokinase, platelet antibody"
Molecular Weight 86 kDa
UniProt Q01813
Research Area Cancer, Metabolism
Comment

Positive Controls: A431 , HeLa , Molt-4 , mouse brain

Restrictions For Research Use only
Format Liquid
Concentration 0.29 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Boulton, Nye, Robbins et al.: "ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF." in: Cell, Vol. 65, Issue 4, pp. 663-75, 1991 (PubMed).

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