Pyruvate Kinase, Liver and RBC (PKLR) (AA 254-574) antibody

Details for Product No. ABIN554103
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms wu:fd15e01, wu:fi37e08, PKLR, cthbp, oip3, pk3, pklr, pkm2, tcb, thbp1, pk1, Pk-1, Pk1, R-PK, PK1, PKL, PKR, PKRL, RPK, Pklg
AA 254-574
(25), (18), (4), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1)
(104), (14), (8), (4), (3), (1), (1)
(72), (34)
(6), (6), (4), (4), (4), (4)
Western Blotting (WB)
(92), (43), (38), (18), (18), (10), (7), (6), (4), (3), (1), (1)
Pubmed 2 references available
Quantity 0.1 mL
Shipping to United States ( )
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Immunogen Recombinant fragment corresponding to a region within amino acids 254 and 574 of
Isotype IgG
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Purified by antigen-affinity chromatography..
Alternative Name PKLR (PKLR Antibody Abstract)
Background The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms: PK1 antibody, PKL antibody, PKR antibody, PKRL antibody, RPK antibody, PKLR antibody, R-type/L-type pyruvate kinase antibody, pyruvate kinase type L antibody, red cell/liver pyruvate kinase antibody, pyruvate kinase 1 antibody, pyruvate kinase isozyme R/L antibody, pyruvate kinase, liver and blood cell antibody, pyruvate kinase isozymes R/L antibody, pyruvate kinase, liver and RBC antibody
Molecular Weight 62 kDa
UniProt P30613
Research Area Cancer, Metabolism

Positive Controls: Jurkat , Raji , K562 , THP-1 , NCI-H929 , mouse liver , rat liver

Restrictions For Research Use only
Format Liquid
Concentration 0.15 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Background publications Krajewski, Bodrug, Krajewska et al.: "Immunohistochemical analysis of Mcl-1 protein in human tissues. Differential regulation of Mcl-1 and Bcl-2 protein production suggests a unique role for Mcl-1 in control of programmed cell death in vivo." in: The American journal of pathology, Vol. 146, Issue 6, pp. 1309-19, 1995 (PubMed).

Kozopas, Yang, Buchan et al.: "MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 8, pp. 3516-20, 1993 (PubMed).

Validation Images
Catalog No. ABIN554103
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)
Did you look for something else?