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JAK3 antibody (Tyrosine-Protein Kinase JAK3) (AA 287-569)

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Synonyms JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK, fae, wil, RATJAK3, JAK
AA 287-569
(15), (15), (13), (13), (12), (8), (7), (7), (6), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
(86), (58), (41), (2), (2), (2), (2), (1), (1), (1)
(68), (23)
This JAK3 antibody is un-conjugated
(3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Western Blotting (WB)
(54), (39), (24), (15), (12), (10), (9), (9), (4), (2), (1), (1), (1)
Pubmed 1 reference available
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Quantity 0.1 mL
Shipping to United States ( )
Immunogen Recombinant fragment contain a sequence corresponding to a region within amino acids 287 and 569 of JAK3
Isotype IgG
Characteristics Cellular Localization: Endomembrane system, Peripheral membrane protein (By similarity)
Purification Purified by antigen-affinity chromatography..
Alternative Name Tyrosine-protein kinase JAK3 (JAK3 Antibody Abstract)
Background The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq]
Synonyms: JAK-3 antibody, JAK3_HUMAN antibody, JAKL antibody, L-JAK antibody, LJAK antibody, JAK3 antibody, tyrosine-protein kinase JAK3 antibody, leukocyte Janus kinase antibody, "Janus kinase 3 (a protein tyrosine kinase, leukocyte) antibody", Janus kinase 3 antibody
Molecular Weight 125 kDa
UniProt P52333
Research Area Signaling, Cytokines, Receptors, Kinases/Phosphatases
Pathways JAK-STAT Signaling, RTK Signaling

Positive Controls: Target recombinant protein

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Davis: "MAPKs: new JNK expands the group." in: Trends in biochemical sciences, Vol. 19, Issue 11, pp. 470-3, 1995 (PubMed).

Catalog No. ABIN554105
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