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CEACAM5 antibody

CEACAM5 Reactivity: Human FACS, IF, WB, IHC (fro), EIA, ICC Host: Mouse Monoclonal 26-3-13 unconjugated
Catalog No. ABIN5541179
  • Target See all CEACAM5 Antibodies
    CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))
    Reactivity
    • 131
    • 21
    • 3
    • 3
    • 1
    Human
    Host
    • 93
    • 37
    • 1
    Mouse
    Clonality
    • 99
    • 32
    Monoclonal
    Conjugate
    • 68
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CEACAM5 antibody is un-conjugated
    Application
    • 78
    • 74
    • 51
    • 49
    • 22
    • 20
    • 14
    • 9
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunocytochemistry (ICC)
    Specificity
    This antibody recognizes exclusively CECAM5.
    Purification
    Protein G Chromatography
    Immunogen
    Extracted protein of CEACAM5. Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
    Clone
    26-3-13
    Isotype
    IgG1
    Top Product
    Discover our top product CEACAM5 Primary Antibody
  • Application Notes
    ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200. Flow Cytometry: 1.2 μg/10 6 cells. Immunofluorescence: 1/200. Western blot: 4 μg/mL. Immunohistochemistry on Cryo -Sections: 1-2 μg/10
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.2 without preservatives
    Preservative
    Without preservative
    Storage
    4 °C,-20 °C
    Storage Comment
    Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Schmitter, Agerer, Peterson, Munzner, Hauck: "Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens." in: The Journal of experimental medicine, Vol. 199, Issue 1, pp. 35-46, (2004) (PubMed).

  • Target
    CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))
    Alternative Name
    cd66e,ceacam5 (CEACAM5 Products)
    Synonyms
    CD66e antibody, CEA antibody, CEACAM5 antibody, CEACAM antibody, 1600029H12Rik antibody, Psg30 antibody, carcinoembryonic antigen related cell adhesion molecule 5 antibody, carcinoembryonic antigen antibody, carcinoembryonic antigen-related cell adhesion molecule 5 antibody, carcinoembryonic antigen-related cell adhesion molecule 8 antibody, carcinoembryonic antigen gene family antibody, CEACAM5 antibody, Ceacam5 antibody, LOC100409241 antibody, Cea antibody
    Background
    CEACAM5 (CEA-related cell adhesion molecule 5, CEA) belongs to the carcinoembryonic antigen (CEA) gene family (1,2). It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein with a Mr of 180,000-200,000 which is most strongly expressed on epithelial cells of the fetal and adult colon and to a minor extent on epithelial cells of the stomach and sweat glands, squamous epithelial cell of the tongue, esophagus and cervix. CEACAM5 is used as a tumor marker for early detection of recurrent disease due to its expression in adenocarcinomas of the colon, lung, breast, stomach and pancreas and in mucinous ovarian carcinomas (3). Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3).
    UniProt
    P06731
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