Selenophosphate Synthetase 2 (SEPHS2) (AA 186-448) antibody

Details for Product No. ABIN554132
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Antigen
Synonyms CG5025, Dmel\\CG5025, Dsps2, SPS2, dSPS2, dsps2, sps2, cb701, zgc:92096, SEPHS2, sps, sephs2, MGC145309, Sps2, Ysg3, SPS2b
Epitope
AA 186-448
(7), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(17), (3)
Host
Rabbit
(18), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
(20), (13), (7), (6), (2), (2), (2), (1), (1)
Pubmed 2 references available
Quantity 0.1 mL
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Catalog No. ABIN554132
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Immunogen Recombinant fragment corresponding to a region within amino acids 186 and 448 of SEPHS2
Isotype IgG
Predicted Reactivity Chimpanzee (100%)
Purification Purified by antigen-affinity chromatography..
Alternative Name SEPHS2
Background This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. This protein itself contains a selenocysteine residue in its predicted active site. The 3' UTR of the gene has a stem-loop secondary structure called a selenocysteine insertion sequence (SECIS) element, which allows UGA to direct the incorporation of selenocysteine rather than signal a translational stop. Alternatively spliced transcripts have been identified, but their biological validity has not been determined. [provided by RefSeq]
Synonyms: SPS2 antibody, SEPHS2 antibody, "selenide, water dikinase 2 antibody", selenium donor protein 2 antibody, selenophosphate synthase 2 antibody, selenophosphate synthetase 2 antibody
Molecular Weight 47 kDa
UniProt Q99611
Comment

Positive Controls: 293T , HeLaS3

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Matsushime, Ewen, Strom et al.: "Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins." in: Cell, Vol. 71, Issue 2, pp. 323-34, 1992 (PubMed).

Graña, Reddy: "Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs)." in: Oncogene, Vol. 11, Issue 2, pp. 211-9, 1995 (PubMed).

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