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High-Mobility Group 20A (HMG20A) (AA 286-347) antibody

Details for Product No. ABIN554170
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Antigen
Synonyms fe47h11, wu:fe47h11, zgc:162335, hmg20a, MGC82871, MGC89476, HMGX1, HMGXB1, 1200004E06Rik, 5730490E10Rik, Hmgxb1, Ibraf, RGD1564760
Epitope
AA 286-347
(7), (4), (2), (2), (2), (1), (1), (1)
Reactivity
Human
(32), (11), (10), (7), (6), (2), (1)
Host
Rabbit
(18), (7), (7)
Clonality
Polyclonal
Application
ELISA
(24), (13), (6), (6), (3), (2), (2)
Pubmed 1 reference available
Quantity 0.1 mL
Shipping to United States (Change)
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Catalog No. ABIN554170
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Immunogen Synthetic peptide corresponding to a region within amino acids 286 and 347 of HMG20A
Isotype IgG
Predicted Reactivity Mouse (100%), Rat (100%), Zebrafish (83%), Rhesus Monkey (100%), Bovine (100%)
Characteristics Cellular Localization: Nucleus
Purification Purified by antigen-affinity chromatography..
Alternative Name HMG20A
Background Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4.
Synonyms: FLJ10739 antibody, HMGX1 antibody, HMGXB1 antibody, HMG20A antibody, high-mobility group 20A antibody, HMG box-containing protein 20A antibody, HMG domain-containing protein HMGX1 antibody, HMG domain-containing protein 1 antibody, high mobility group protein 20A antibody, HMG box domain containing 1 antibody
Molecular Weight 40 kDa
UniProt Q9NP66
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Comment

Positive Controls: Synthetic peptide: 1:8,000

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Baker, Markowitz, Fearon et al.: "Suppression of human colorectal carcinoma cell growth by wild-type p53." in: Science (New York, N.Y.), Vol. 249, Issue 4971, pp. 912-5, 1990 (PubMed).

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