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High-Mobility Group 20A (HMG20A) (AA 286-347) antibody

Details for Product No. ABIN554170, Supplier: Login to see
Antigen
  • fe47h11
  • wu:fe47h11
  • zgc:162335
  • hmg20a
  • MGC82871
  • MGC89476
  • HMGX1
  • HMGXB1
  • 1200004E06Rik
  • 5730490E10Rik
  • Hmgxb1
  • Ibraf
  • RGD1564760
Epitope
AA 286-347
20
10
4
3
2
2
2
2
1
1
1
Reactivity
Human
71
21
18
11
8
4
1
1
1
1
Host
Rabbit
31
20
20
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
Application
ELISA
46
31
29
12
7
3
2
1
1
Supplier
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Immunogen Synthetic peptide corresponding to a region within amino acids 286 and 347 of HMG20A
Isotype IgG
Predicted Reactivity Mouse (100%), Rat (100%), Zebrafish (83%), Rhesus Monkey (100%), Bovine (100%)
Characteristics Cellular Localization: Nucleus
Purification Purified by antigen-affinity chromatography..
Alternative Name HMG20A (HMG20A Antibody Abstract)
Background Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4.
Synonyms: FLJ10739 antibody, HMGX1 antibody, HMGXB1 antibody, HMG20A antibody, high-mobility group 20A antibody, HMG box-containing protein 20A antibody, HMG domain-containing protein HMGX1 antibody, HMG domain-containing protein 1 antibody, high mobility group protein 20A antibody, HMG box domain containing 1 antibody
Molecular Weight 40 kDa
UniProt Q9NP66
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Pathways
Comment

Positive Controls: Synthetic peptide: 1:8,000

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Background publications Baker, Markowitz, Fearon et al.: "Suppression of human colorectal carcinoma cell growth by wild-type p53." in: Science (New York, N.Y.), Vol. 249, Issue 4971, pp. 912-5, 1990 (PubMed).