LIM and SH3 Protein 1 (LASP1) (AA 1-44) antibody

Details for Product No. ABIN554199
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Antigen
Synonyms lasp1, MGC53336, LASP1, MGC89667, Lasp-1, MLN50, AA408629, Def-4, SH3P6, Tg(Col1a1-lacZ)1Ngma, fb92f05, wu:fb92f05, zgc:77542, lasp-1, mln50
Epitope
AA 1-44
(14), (8), (7), (7), (3), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(45), (9), (9), (7), (4), (2), (2), (2), (2), (1)
Host
Rabbit
(25), (15), (9)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(47), (26), (5), (2), (1)
Pubmed 5 references available
Quantity 0.1 mL
Shipping to United States (Change)
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Catalog No. ABIN554199
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Immunogen Synthetic peptide corresponding to a region within amino acids 1 and 44 of LASP1
Isotype IgG
Predicted Reactivity Mouse (100%), Rat (100%), Xenopus laevis (92%), Xenopus Tropicalis (92%), Rabbit (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (92%)
Characteristics Cellular Localization: Cytoplasm , cell cortex (By similarity) , cytoskeleton (By similarity)
Purification Purified by antigen-affinity chromatography..
Alternative Name LASP1
Background This gene encodes a member of a LIM protein subfamily characterized by a LIM motif and a domain of Src homology region 3. The encoded protein functions as an actin-binding protein and possibly in cytoskeletal organization. [provided by RefSeq]
Synonyms: Lasp-1 antibody, MLN50 antibody, LASP1 antibody, LIM and SH3 domain protein 1 antibody, MLN 50 antibody, metastatic lymph node gene 50 protein antibody, LIM and SH3 protein 1 antibody
Molecular Weight 30 kDa
UniProt Q14847
Research Area Signaling, Cytoskeleton, Microfilaments
Comment

Positive Controls: LASP1 tansfected 293T cell

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Sun, Baltimore: "An inhibitory domain of E12 transcription factor prevents DNA binding in E12 homodimers but not in E12 heterodimers." in: Cell, Vol. 64, Issue 2, pp. 459-70, 1991 (PubMed).

Whelan, Cordle, Henderson et al.: "Identification of a pancreatic beta-cell insulin gene transcription factor that binds to and appears to activate cell-type-specific expression: its possible relationship to other cellular factors that bind to a common insulin gene sequence." in: Molecular and cellular biology, Vol. 10, Issue 4, pp. 1564-72, 1990 (PubMed).

Murre, McCaw, Baltimore: "A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins." in: Cell, Vol. 56, Issue 5, pp. 777-83, 1989 (PubMed).

Lenardo, Pierce, Baltimore: "Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility." in: Science (New York, N.Y.), Vol. 236, Issue 4808, pp. 1573-7, 1987 (PubMed).

Bain, Gruenwald, Murre: "E2A and E2-2 are subunits of B-cell-specific E2-box DNA-binding proteins." in: Molecular and cellular biology, Vol. 13, Issue 6, pp. 3522-9, 1993 (PubMed).

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