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Oxysterol Binding Protein 2 (OSBP2) (AA 854-916) antibody

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Synonyms ORP-4, ORP4, OSBPL1, OSBPL4, 1700095P05Rik, C630001G20Rik, Gm244, RGD1309479
AA 854-916
(12), (2), (1), (1), (1), (1), (1)
(34), (16), (16), (3), (3), (3), (1), (1)
(19), (15), (1)
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
(15), (11), (11), (5)
Pubmed 3 references available
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Quantity 0.1 mL
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Immunogen Synthetic peptide corresponding to a region within amino acids 854 and 916 of OSBP2
Isotype IgG
Predicted Reactivity Human (100%), Mouse (92%), Rat (92%), Bovine (92%)
Characteristics Cellular Localization: Membrane, Peripheral membrane protein
Purification Purified by antigen-affinity chromatography..
Alternative Name OSBP2 (OSBP2 Antibody Abstract)
Background Oxysterols are byproducts of cholesterol that can have cytotoxic effects on many cell types. The membrane-bound protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternate transcriptional splice variants have been observed but have not been fully characterized. [provided by RefSeq]
Synonyms: ORP-4 antibody, ORP4 antibody, OSBPL1 antibody, OSBPL4 antibody, OSBP2 antibody, OSBP-related protein 4 antibody, oxysterol-binding protein-related protein 4 antibody, oxysterol binding protein-like 1 antibody, oxysterol binding protein-related protein 4 antibody, oxysterol-binding protein 2 antibody, oxysterol binding protein 2 antibody
Molecular Weight 101 kDa
UniProt Q969R2
Research Area Signaling, Metabolism

Positive Controls: Synthetic peptide: 1:8,000

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Dyson, Dembski, Fattaey et al.: "Analysis of p107-associated proteins: p107 associates with a form of E2F that differs from pRB-associated E2F-1." in: Journal of virology, Vol. 67, Issue 12, pp. 7641-7, 1993 (PubMed).

Saito, Helin, Valentine et al.: "Amplification of the E2F1 transcription factor gene in the HEL erythroleukemia cell line." in: Genomics, Vol. 25, Issue 1, pp. 130-8, 1995 (PubMed).

Nevins: "E2F: a link between the Rb tumor suppressor protein and viral oncoproteins." in: Science (New York, N.Y.), Vol. 258, Issue 5081, pp. 424-9, 1992 (PubMed).

Catalog No. ABIN554213
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