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Sorting Nexin 10 (SNX10) (AA 139-201) antibody

Details for Product No. ABIN554218, Supplier: Login to see
Antigen
  • LOC100230219
  • OPTB8
  • 2410004M09Rik
Epitope
AA 139-201
2
2
2
1
1
Reactivity
Human
21
16
13
Host
Rabbit
16
6
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA
12
11
3
3
1
Supplier
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Immunogen Synthetic peptide corresponding to a region within amino acids 139 and 201 of SNX10
Isotype IgG
Predicted Reactivity Human (100%), Rhesus Monkey (100%)
Purification Purified by antigen-affinity chromatography..
Alternative Name Sorting nexin-10 (SNX10) (SNX10 Antibody Abstract)
Background This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. This gene encodes a protein whose function has not been determined. [provided by RefSeq]
Synonyms: MGC33054 antibody, SNX10 antibody, sorting nexin-10 antibody, sorting nexin 10 antibody
Molecular Weight 24 kDa
UniProt Q9Y5X0
Pathways
Comment

Positive Controls: Synthetic peptide: 1:8,000

Restrictions For Research Use only
Format Liquid
Concentration 0.37 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Product cited in: Krajewski, Tanaka, Takayama et al.: "Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes." in: Cancer research, Vol. 53, Issue 19, pp. 4701-14, 1993 (PubMed).

Veis, Sentman, Bach et al.: "Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 5, pp. 2546-54, 1993 (PubMed).

Novack, Korsmeyer: "Bcl-2 protein expression during murine development." in: The American journal of pathology, Vol. 145, Issue 1, pp. 61-73, 1994 (PubMed).

Reed, Tsujimoto, Alpers et al.: "Regulation of bcl-2 proto-oncogene expression during normal human lymphocyte proliferation." in: Science (New York, N.Y.), Vol. 236, Issue 4806, pp. 1295-9, 1987 (PubMed).

Background publications Miyashita, Krajewski, Krajewska et al.: "Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo." in: Oncogene, Vol. 9, Issue 6, pp. 1799-805, 1994 (PubMed).

Tsujimoto, Cossman, Jaffe et al.: "Involvement of the bcl-2 gene in human follicular lymphoma." in: Science (New York, N.Y.), Vol. 228, Issue 4706, pp. 1440-3, 1985 (PubMed).

Hockenbery, Nuñez, Milliman et al.: "Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death." in: Nature, Vol. 348, Issue 6299, pp. 334-6, 1991 (PubMed).