RPS6KA2 antibody (AA 415-734)

Catalog No. ABIN5542368

Product Details anti-RPS6KA2 Antibody

Target: RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))

Binding Specificity: AA 415-734

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This RPS6KA2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purification: purified

Immunogen: Purified recombinant fragment of human RPS6KA2 (AA: 415-734) expressed in E. coli.

Clone: 3C4C8

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for RPS6KA2

Target: RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))

Alternative Name: RPS6KA2 (RPS6KA2 Products)

Synonyms: HU-2 antibody, MAPKAPK1C antibody, RSK antibody, RSK3 antibody, S6K-alpha antibody, S6K-alpha2 antibody, p90-RSK3 antibody, pp90RSK3 antibody, 90kDa antibody, D17Wsu134e antibody, Rps6ka-rs1 antibody, Rsk3 antibody, p90rsk antibody, pp90rsk antibody, ribosomal protein S6 kinase A2 antibody, ribosomal protein S6 kinase, polypeptide 2 antibody, Rps6ka2 antibody, RPS6KA2 antibody

Background:

Description: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Aliases: RSK, HU-2, RSK3, p90-RSK3, pp90RSK3, MAPKAPK1C, S6K-alpha, S6K-alpha2

Molecular Weight: 83.2 kDa

Gene ID: 6196

HGNC: 6196

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Activation of Innate immune Response, Toll-Like Receptors Cascades