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Interleukin 16 (IL16) (AA 1-45) antibody

Details for Product No. ABIN554549, Supplier: Login to see
Antigen
  • IL16
  • LCF
  • NIL16
  • PRIL16
  • prIL-16
  • mKIAA4048
  • IL-16
Epitope
AA 1-45
20
9
6
5
5
5
5
4
3
3
3
2
2
1
1
1
1
1
Reactivity
Human
165
34
28
2
2
Host
Rabbit
107
69
3
1
1
Clonality
Polyclonal
Conjugate
Un-conjugated
8
4
2
2
2
1
1
Application
ELISA
120
106
29
17
16
15
13
11
7
4
4
3
2
2
1
Supplier
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Immunogen Synthetic peptide corresponding to a region within amino acids 1 and 45 of IL16
Isotype IgG
Predicted Reactivity Human (100%), Chimpanzee (100%)
Characteristics Cellular Localization: Interleukin-16: Secreted , Isoform 1: Cytoplasm , Isoform 3: Cytoplasm , Nucleus
Purification Purified by antigen-affinity chromatography..
Alternative Name Interleukin-16 / IL16 (IL16 Antibody Abstract)
Background The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms: FLJ16806 antibody, FLJ42735 antibody, FLJ44234 antibody, LCF antibody, NIL16 antibody, PRIL16 antibody, prIL-16 antibody, IL16 antibody, neuronal interleukin 16 antibody, lymphocyte chemoattractant factor antibody, pro-interleukin-16 antibody, prointerleukin 16 antibody, interleukin 16 (lymphocyte chemoattractant factor) antibody
Molecular Weight 142 kDa
UniProt Q14005
Pathways
Comment

Positive Controls: Synthetic peptide: 1:8,000

Restrictions For Research Use only
Format Liquid
Concentration 0.09 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid multiple freeze-thaw cycles.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below.
Background publications Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, 1996 (PubMed).