OLIG1 antibody

Catalog No. ABIN372692

Product Details anti-OLIG1 Antibody

Target: OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OLIG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody recognizes the ~27 kDa Olig1 protein in Western blots.

Cross-Reactivity (Details): Species reactivity (tested):Mouse and Rat.

Purification: Protein A Chromatography.

Immunogen: Recombinant Mouse Olig1.

Isotype: IgG

Application Details

Application Notes: Western blot: 1/3000. Immunohistochemistry: 1/1000. Immunocytochemistry: 1/1000. Immunoprecipitation: 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 mM Glycine, 200 mM Tris, pH 8.0 without preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at-20 °C.

Target Details for OLIG1

Target: OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))

Alternative Name: OLIG1 (OLIG1 Products)

Synonyms: OLIG1 antibody, BHLHB6 antibody, BHLHE21 antibody, AI836478 antibody, AW494459 antibody, Bhlhb6 antibody, Olg-1 antibody, Oligo1 antibody, bHLHe21 antibody, Olg1 antibody, oligodendrocyte transcription factor 1 antibody, OLIG1 antibody, Olig1 antibody

Background: Olig genes have been identified as the earliest known markers of oligodendrocyte lineage determination to date (Zhou et al., 2000). Olig1 is a transcription factor which promotes formation and maturation of oligodendrocytes, especially within the brain. It is expressed in the ventral spinal cord as early as 9.5 dpc and by 15.5 dpc, olig1 is dispersed throughout the gray matter. In the postnatal brain, it is present preferentially in the white matter, such as corpus callosum and cerebellar medulla. Olig1 has been demonstrated as necessary in the repair of brain lesions in patients with multiple sclerosis (Arnett et al. 2004).Synonyms: OLIG-1, Oligo1, Oligodendrocyte transcription factor 1

Gene ID: 60394

NCBI Accession: NP_068538

UniProt: Q9WUQ3