STK26/MST4 antibody (C-Term)

Catalog No. ABIN374186

Product Details anti-STK26/MST4 Antibody

Target: STK26/MST4 (MST4) (Serine/threonine-Protein Kinase MST4 (MST4))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This STK26/MST4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KLIEKFQKCS ADESP

Specificity: This antibody detects MST4 at C-term.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_057626.2, NP_001035918.1, NP_001035917.1 Genename: RP6-213H19.1

Application Details

Application Notes: Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-1.5 μg/mL. Approx 50 kDa band observed in lysates of cell lines HEK293,HepG2 and Jurkat (calculated MW of 46.0 kDa according to NP_057626.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Target Details for STK26/MST4

Target: STK26/MST4 (MST4) (Serine/threonine-Protein Kinase MST4 (MST4))

Alternative Name: MST4 (MST4 Products)

Synonyms: Mst4 antibody, MASK antibody, RGD1563568 antibody, serine/threonine kinase 26 antibody, Stk26 antibody, STK26 antibody

Background: Novel human Ste20-related kinase Mst4 is biologically active in the activation of MEK/ERK pathway and in mediating cell growth and transformation. It is pro apoptotic and is highly expressed in placenta, thymus, and peripheral blood leukocytes. Interaction with Golgi matrix protein GOLGA2 results in autophosphorylation on Thr-178, possibly as a consequence of stabilization of dimer formation. This may also be activated by C terminal cleavage.Synonyms: MASK, Mst3 and SOK1-related kinase, RP6-213H19.1, STE20-like protein kinase 4, Serine/threonine-protein kinase MST4

Gene ID: 51765

NCBI Accession: NP_057626

UniProt: Q9P289