Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

ANTXR1 antibody (C-Term)

ANTXR1 Reactivity: Human WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN374464
  • Target See all ANTXR1 Antibodies
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Binding Specificity
    • 15
    • 9
    • 8
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 76
    • 40
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 70
    • 3
    • 3
    Goat
    Clonality
    • 73
    • 3
    Polyclonal
    Conjugate
    • 35
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ANTXR1 antibody is un-conjugated
    Application
    • 48
    • 30
    • 15
    • 13
    • 13
    • 11
    • 9
    • 5
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Specificity
    This antibody reacts to Anthrax toxin receptor 1.
    Cross-Reactivity (Details)
    Species reactivity (expected):Rat, Bovine, Canine.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogen
    Peptide with sequence C-RAPPPSRPPPRPSV, from the C Terminus of the protein sequence
    Top Product
    Discover our top product ANTXR1 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/64000. Western blot: 0.2 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0,5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Alternative Name
    Anthrax Toxin Receptor 1 (ANTXR1 Products)
    Synonyms
    ANTXR1 antibody, ATR antibody, TEM8 antibody, 2310008J16Rik antibody, 2810405N18Rik antibody, Antrx1 antibody, Tem8 antibody, anthrax toxin receptor 1 antibody, ANTXR1 antibody, Antxr1 antibody
    Background
    TEM8 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has also been shown to be a docking protein or receptor for Bacillus anthracistoxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor(EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants have been described.Synonyms: ANTXR1, ATR, TEM8, Tumor endothelial marker 8
    Gene ID
    84168, 9606
    UniProt
    Q9H6X2
You are here:
Support