EFHD2 antibody (C-Term)

Catalog No. ABIN374490

Product Details anti-EFHD2 Antibody

Target: EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This EFHD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This anitbody reacts to EFHD2.

Cross-Reactivity (Details): Species reactivity (expected):Rat, Canine, Bovine.
Species reactivity (tested):Human, Mouse.

Purification: Affinity chromatography

Immunogen: Peptide with sequence CAAFKELQSTFK, from the C Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/16000. Western blot: 0.1 - 0.3 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-EFHD2 antibody (ABIN374490)

Brachs, Lang, Buslei, Purohit, Fürnrohr, Kalbacher, Jäck, Mielenz: "Monoclonal antibodies to discriminate the EF hand containing calcium binding adaptor proteins EFhd1 and EFhd2." in: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 4, pp. 237-45, (2013) (PubMed).

Chen, Li, Meng, Fan, Song, Wang, Zhu, Guo, Zhang, Shi: "Upregulation of B7-H1 expression is associated with macrophage infiltration in hepatocellular carcinomas." in: Cancer immunology, immunotherapy : CII, Vol. 61, Issue 1, pp. 101-8, (2012) (PubMed).

Napolitano, Pasqualetti, Usiello, Santini, Pacini, Sciamanna, Errico, Tassone, Di Dato, Martella, Cuomo, Fisone, Bernardi, Mandolesi, Mercuri, Standaert, Pisani: "Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 dystonia." in: Neurobiology of disease, Vol. 38, Issue 3, pp. 434-45, (2010) (PubMed).

Wang, Paramasivam, Thomas, Bai, Kaminen-Ahola, Kere, Voskuil, Rosen, Galaburda, Loturco: "DYX1C1 functions in neuronal migration in developing neocortex." in: Neuroscience, Vol. 143, Issue 2, pp. 515-22, (2006) (PubMed).

Target Details for EFHD2

Target: EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

Alternative Name: EFHD2 (EFHD2 Products)

Synonyms: SWS1 antibody, efhd2 antibody, EFHD2 antibody, MGC131292 antibody, 2600015J22Rik antibody, AA408606 antibody, D4Wsu27e antibody, si:dkey-72l14.9 antibody, wu:fb80e07 antibody, EF-hand domain family member D2 antibody, EF-hand domain family, member D2 antibody, EF-hand domain family member D2 L homeolog antibody, EF hand domain containing 2 antibody, EFHD2 antibody, Efhd2 antibody, efhd2 antibody, efhd2.L antibody

Background: EFDH2 is a protein whose gene expression is increased in purified populations of CD8 lymphocytes, when compared to CD19 and CD4 lymphocytes. EFDH2 contains two potential EF-hand domains, and therefore may have a role in calcium signaling. Its predominant presence in CD8 lymphocytes suggests that it may be involved in functions that are important for cytotoxic lymphocytes.Synonyms: EF-hand domain-containing protein D2, SWS1, Swiprosin 1, Swiprosin-1

Gene ID: 79180

NCBI Accession: NP_077305

UniProt: Q96C19