PIP antibody (Internal Region)

Catalog No. ABIN374677

Product Details anti-PIP Antibody

Target: PIP (Prolactin-Induced Protein (PIP))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This PIP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequence: C-GANKAQDNTR K

Specificity: This antibody recogniozes GCDFP15.

Purification: Immunoffinity Chromatography

Immunogen: Synthetic peptide from an internal region of Human PIP. Genename: PIP

Application Details

Application Notes: Peptide ELISA: 1/128000. Western Blot: 0.3 - 1 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide and 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PIP

Target: PIP (Prolactin-Induced Protein (PIP))

Alternative Name: PIP / GCDFP15 (PIP Products)

Synonyms: GCDFP-15 antibody, GCDFP15 antibody, GPIP4 antibody, GP17 antibody, mSMGP antibody, prolactin induced protein antibody, PIP antibody, Pip antibody

Background: Gross cystic disease is a common premenopausal disorder in which gross cysts are the predominant pathologic lesion. It is characterized by production of a fluid secretion which accumulates in the breast cysts. Gross cystic disease fluid is a pathologic secretion from breast composed of several glycoproteins, including a unique 15 kDa monomer protein, GCDFP 15. The cells within the body that produce GCDFP 15 appear to be restricted primarily to those with apocrine function. Studies have found GCDFP 15 to be a highly specific and sensitive marker for breast cancer.Synonyms: GCDFP-15, GPIP4, Gross cystic disease fluid protein 15, Prolactin-induced protein, Prolactin-inducible protein, SABP, Secretory actin-binding protein, gp17

Gene ID: 5304, 9606

UniProt: P12273